Fatores de virulência de Staphylococcus aureus

Autores

  • Atzel Candido Acosta Universidade Federal Rural de Pernambuco (UFRPE)
  • Mateus Matiuzzi Costa Universidade Federal do Vale do São Francisco (Univasf)
  • José Wilton Pinheiro Junior Universidade Federal Rural de Pernambuco (UFRPE)
  • Rinaldo Aparecido Mota Universidade Federal Rural de Pernambuco (UFRPE)

DOI:

https://doi.org/10.26605/medvet-n4-1955

Resumo

Nas últimas décadas, Staphylococcus aureus (S. aureus) adquiriu considerável importância relacionada à saúde animal e humana pela elevada patogenicidade e aumento na prevalência de cepas multirresistentes aos antibióticos. Sua elevada patogenicidade está relacionada com mecanismos multifatoriais e complexos determinados pela capacidade da bactéria de expressar uma variedade de fatores de virulência que facilitam a ocorrência de doenças. Objetivou-se com esta revisão compilar informações referentes aos fatores de virulência associados à superfície ou secretados por S. aureus que promovem adesão aos componentes da matriz extracelular do hospedeiro, danificam células hospedeiras e interferem no sistema imunológico. A implementação de estratégias para a prevenção e terapia em infecções associadas a S. aureus exige o aprofundamento dos estudos nos diferentes mecanismos de ação dos fatores de virulência.

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07-05-2018

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Acosta, A. C., Matiuzzi Costa, M., Pinheiro Junior, J. W., & Mota, R. A. (2018). Fatores de virulência de Staphylococcus aureus. Medicina Veterinária, 11(4), 252–269. https://doi.org/10.26605/medvet-n4-1955

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Medicina Veterinária Preventiva