Mediastinal compression in a dog secondary to multiple cartilaginous exostoses in the rib: case report

Authors

DOI:

https://doi.org/10.26605/medvet-v19n4-7091

Keywords:

Osteochondroma, regurgitation, cough, tomography, radiology

Abstract

We report the case of an 8-year-old male Poodle dog, presenting regurgitation and chronic cough, who underwent radiographic and tomographic studies, which revealed the presence of polyostotic bone nodules of mixed radiopacity. From the imaging exams, it was possible to visualize exostosis starting from the first right rib, projecting into the thorax and causing displacement of the cranial mediastinum, with consequent esophageal and tracheal displacement. Due to neoplastic compression, the dog presented marked deviation of the cranial mediastinum, tracheal dislocation and gas dilatation of the esophagus accompanied by ventrolateral deviation and tortuosity. Based on the radiographic findings, osteochondroma (multiple cartilaginous exostosis) was suspected as the main differential diagnosis, and the diagnosis was confirmed after histopathological analysis. The rare occurrence of this disease in dogs and the atypical clinical signs in this patient stand out, signs that are unprecedented in veterinary literature. The importance of imaging and histopathological exams for diagnostic conclusion, therapeutic planning and prognosis establishment is also highlighted. The surgery was successful and there has been no return of clinical signs or tumor recurrence to date.

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References

Azizi, S. et al. Multiple cartilaginous exostoses of rib in dog: a case report. Comparative Clinical Pathology, 33(1): 1-5, 2023.

Bezerra, J.A.B. et al. Multiple cartilaginous exostoses in a pediatric dog. Acta Scientiae Veterinariae, 47(1): 1-5, 2019.

Bovée, J.V.M.G. et al. Intermediate grade osteosarcoma and chondrosarcoma arising in an osteochondroma: a case report of a patient with hereditary multiple exostoses. Journal of Clinical Pathology, 55(3): 226–229, 2002.

Cordella, A. et al. CT features of primary bone neoplasia of the thoracic wall in dogs. Veterinary Radiology & Ultrasound, 64(4): 605-614, 2023.

Czerwik, A. et al. Multiple cartilaginous exostoses in a swiss mountain dog causing thoracolumbar compressive myelopathy. Acta Veterinaria Scandinavica, 61(32): 1-6, 2019.

De Brot, S. et al. Occurrence of osteochondromatosis (multiple cartilaginous exostoses) in a domestic pig (Sus scrofa domesticus). Journal of Veterinary Diagnostic Investigation, 25(5): 599-602, 2013.

Detcharoenyos, N.; Pattanapon, N.; Petchdee, S. Management of spinal osteochondroma in young golden retriever. Advances in Animal and Veterinary Sciences, 10(7): 1513-1517, 2022.

Dixon, J.J.; Anderson, J.D.C. Radiographic, computed tomographic and CT myelographic findings of an extensive cervical osteochondroma resulting in spinal cord compression at the atlanto?occipital junction. Equine Veterinary Education, 33(3): 33-37, 2021.

Fahim, D.K. et al. Periosteal chondroma of the pediatric cervical spine: case report. Journal of Neurosurgery: Pediatrics, 3(2): 151-156, 2009.

Feitosa, F.L.F. Exame Físico Geral ou de Rotina. In: ______. Semiologia Veterinária: A arte do diagnóstico. 3ª ed. Araçatuba: Roca LTDA, 2014. p. 51-57.

Franch, J. et al. Multiple cartilaginous exostosis in a golden retriever cross-bred puppy: clinical, radiographic and backscattered scanning microscopy findings. Veterinary and Comparative Orthopaedics and Traumatology, 18(3): 189–193, 2005.

Friedenberg, S.G. et al. A de novo mutation in the EXT2 gene associated with osteochondromatosis in a litter of american staffordshire terriers. Journal of Veterinary Internal Medicine, 32(3): 986–992, 2018.

Garcia, S.A. et al. Osteochondroma pathogenesis: mouse models and mechanistic insights into interactions with retinoid signaling. The American Journal of Pathology, 191(12): 2042–2051, 2021.

Gómez, A. et al. Feline osteochondromatosis in a 12-year-old feline leukaemia virus-negative cat. Journal of Comparative Pathology, 205: 24-26, 2023.

Green, E.M.; Adams, W.M.; Steinberg, H. Malignant transformation of solitary spinal osteochondroma in two mature dogs. Veterinary Radiology & Ultrasound, 40(6): 634-637, 1999.

Grobman, M.; Reinero, C.A. One health review of aerodigestive disease in dogs. Journal of Veterinary Internal Medicine, 37(3): 817-834, 2023.

Ha, T.H. et al. Hereditary multiple exostoses: a case report and literature review. SAGE Open Medical Case Reports, 10: 1-11, 2022.

Jacobson, L.S.; Kiberger, R.M. Canine multiple cartilaginous exostoses: Unusual manifestations and a review of the literature. Journal of the American Animal Hospital Association, 32(1): 45–51, 1996.

Kitsoulis, P. et al. Osteochondromas: review of the clinical, radiological and pathological features. In Vivo, 22(5): 633-646, 2008.

Laeta, M. et al. Osteochondromatosis (multiple cartilaginous exostoses) in an immature killer whale Orcinus orca. Diseases of Aquatic Organisms, 134(3): 209-213, 2019.

Leonardi, L. Bone tumors in domestic animals: comparative clinical pathology. 1st ed. Berlim: Springer Cham, 2022. v.1, 208p.

Menezes, M.P. et al. Multiple cartilaginous exostoses causing severe cervical myelopathy in a puppy dog. VCOT Open, 4(1): 1-4, 2021.

Ricker, Z.H.; Vinayak, A.; Kerwin, S.C. What is your diagnosis? Multiple cartilaginous exostoses. Journal of the American Veterinary Medical Association, 229(7): 1085-1086, 2006.

Santana, A.C.F. et al. Hereditary multiple exostosis with malignant transformation: a case report. Brazilian Journal of Health Review, 4(5): 21917-21923, 2021.

Silva, C.I.F. et al. Lumbar myelopathy caused by multiple cartilaginous exostoses in a dog, Topics in Companion Animal Medicine, 44: 1-3, 2021.

Silva, J.E. et al. Chondrosarcoma secondary to hereditary multiple osteochondromas with spinal cord compression: a case report and systematic review. Surgical Neurology International, 14(387): 1-5, 2023.

Thompson, K.G.; Dittmer, K.E. Tumors of Bone. In: Meuten, D.J. Tumors in Domestic Animals. 5th ed. New Jersey: John Wiley & Sons, 2017. p.356-424.

Ullal, T.V. et al. A comparative assessment of the diagnosis of swallowing impairment and gastroesophageal reflux in canines and humans. Frontiers in Veterinary Science, 9: 1-38, 2022.

Watine, S. et al. Resolution of chylothorax after resection of rib chondroma in a dog. Journal of Small Animal Practice, 44(12): 546–549, 2003.

Published

2025-12-31

How to Cite

Novaes, R. C. C., Oliveira, A. S. de, Rocha, J. A. da S., Siqueira Filho, R. S. de, Lima, D. C. de A., Souza, W. J. da S. e, … Costa, F. S. (2025). Mediastinal compression in a dog secondary to multiple cartilaginous exostoses in the rib: case report. Medicina Veterinária, 19(4), 338–348. https://doi.org/10.26605/medvet-v19n4-7091

Issue

Section

Small Animal Clinic and Surgery

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